Die Partner von TRAIN verfügen über die komplette Ausrüstung und Expertise, um an jedem Entwicklungsschritt der pharmazeutischen Wertschöpfungskette den entscheidenden Mehrwert für Ihre Projekte in den Bereichen
- Small Molecules und
Wir unterstützen Sie mit einer initialen Einschätzung, um zu prüfen, ob das kommerzielle Potenzial Ihres Lead Kandidaten für eine professionelle Entwicklung spricht.
Im Anschluss führen unsere erfahrenen Projekt Manager Ihr Projekt durch alle präklinischen Phasen zu einem klinischen Proof-of-Concept in unserer Phase I/II Prüfeinheit.
Die Bandbreite möglicher Interaktionen mit uns reicht von akademischen Forschungskooperationen bis zu Fee-for-service Vereinbarungen.
Research & Discovery
Clinical Phase I to II
Validation in Mice
Helmholtz Center for Infection Research (HZI)
The HZI activities are focussed in the area of Infection & Immunity. The main goal is to elucidate the processes
of microbial pathogenesis and host response to infection, in order to develop new tools and strategies to
prevent and treat infectious diseases. There are collaboration opportunities in the areas of natural products,
pharmaceutical research, vaccinology, immunology and structural biology.
Hit to Lead
Leibniz University Hannover (LUH)
The institute of Organic Chemistry at LUH has a focus on synthetic chemistry, research in oncology and infectious diseases, as well as the isolation and identiﬁcation of novel APIs (e.g. plant-derived) via innovative screening and development technologies.
R&D in ATMPs, Biologics & Small Molecules
in a broad portfolio of indications
Medical School Hannover (MHH)
Areas of specialization of the MHH include the entire range of superior services provided by a major medical facility.
In addition the MHH is internationally most renowned for transplant medicine and related immunological ﬁelds. Other focus areas are:
- Disorders of the immune system and infectious diseases (particularly of the liver)
- Oncology, pediatric and adult (male and female)
- Cardiac, vascular and respiratory medicine
- Restorative surgery, e.g. accident and emergency surgery, urology, and high-tech hearing aids (cochlear implants)
ATMPs – Deveplopment of a broad variety of Cell Therapy and Gene Therapy approaches.
Small Molecules – Argyrin
Fraunhofer Institute of Toxicology and Experimental Medicine (ITEM)
Services offered range from studies in the areas of occupational and environmental toxicology and consumer protection up to pre-clinical and clinical drug research and development, from allergy and asthma research up to the assessment and registration of chemicals, biocides and pesticides.
Diagnostics & Therapeutics
University of Veterinary Medicine Hannover (TiHo)
Services including clinical treatment of patients and pathological and diagnostic examinations of materials submitted; veterinary care of agricultural stock and consultation on all questions of animal husbandry, particularly the diagnosis of infections; and chemical, biochemical, or toxicological analyses.
Technical University Carolo-Wilhelmina at Braunschweig (TU BS)
The Technical University at Braunschweig offers technical and mathematical knowhow in engineering as well as classical and molecular biology. Scientists at the Biocenter of TU BS are specialized in research in microbiology, genetics and cell biology.
Translational Research & Regulatory Expertise
TWINCORE – Center for Experimental and Clinical Infection Research
At TWINCORE medical personnel and basic research scientists from various disciplines conduct translational infection research side by side. Scientists at TWINCORE support the development of new strategies to combat infectious diseases by creating a scientiﬁc basis for risk assessment in advance of the clinical trials.
Project Management, Regulatory Interaction, Legal Sponsor of Clinical Trials
Vakzine Projekt Management GmbH (VPM)
acquires promising vaccine candidates and biopharmaceuticals from academia, develops them with a consortium of partners and commercializes the results
Establishment of German vaccines map and selection of ﬁve development projects
Successful development of VPM1002, a gene-modiﬁed live tuberculosis vaccine, from bench to bedside in four years
GPM Manufacturing Practice
ATMP Advanced Therapy Medicinal Product