What is translation?


Translational research represents the interface between basic research and clinical development. The goal is to enable the latest findings from basic research to lead to new therapies or diagnostic procedures for patients in the shortest of times. At the same time, questions that arise during the clinical practice are fed back to basic research for systematic analysis.





In the “Translationsallianz in Niedersachsen” (translational alliance in Lower Saxony), leading universities, clinical centers, non-university research institutions, and companies bundle their know-how and infrastructures in the area of biomedicine. The resulting network aims at shortening the process of bringing findings from basic research to application at the patient – in the form of new methods of diagnosis, therapy or prevention.


Supported by the Ministry for Science and Culture of Lower Saxony (MWK), new centres and institutions emerge from this cooperation. These translational centres fill the gaps between basic research and clinical practice – and thereby help completing the chain of medical development in Lower Saxony.


The afore-mentioned TRAIN centres are:


At  TWINCORE in Hannover, scientists of  TWINCORE,  MHH, and  HZI work together in several disciplines to answer questions in the field of infection research. They form the interface between basic research and clinic in order to develop new therapies and diagnostic methods.



Braunschweig Integrated Centre of Systems Biology

At the Braunschweig Integrated Centre of Systems Biology (BRICS), the TU Braunschweig and the HZI combine their expertise in the fields of systems biology and bioinformatics. Their aim is to gain new insights into and enhance the predictability of complex biological processes by creating an interaction between mathematical models and experiments.



Clinical Research Centre Hannover

The Clinical Research Center Hannover (CRC Hannover) is the only medical research center of its kind in Germany, operated by three partners: Fraunhofer ITEM, Hannover Medical School, and Helmholtz Center for Infection Research. Early-phase and proof-of-concept studies are conducted at the CRC Hannover to test new drugs and therapeutic approaches for safety and efficacy. In addition, the Helmholtz Center for Infection Research is using the CRC Hannover as study center for the “National Cohort”, Germany’s largest nationwide population study.

Centre of Drug Research

The Centre of Drug Research (Niedersächsisches Wirkstoffzentrum) is a collaboration between three research centres: the Centre of Biomolecular Drug Research (BMWZ), the Drug Research and Functional Genomics Centre (DRFG) and the Zentrum für Pharmaverfahrenstechnik (PVZ). In these centres researchers of the Leibniz University Hannover, the TU Braunschweig and the HZI work side by side to search for and develop new drugs against infections and tumors.Their research is focused on studies of chemical and biological natural products.